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Data input

load_10x_lymphnode()
Load the 10x Human Lymph Node Visium dataset as a Seurat object
load_10x_spatial_set()
Load a set of 10x spatial datasets
merge_spatial_seurat_list()
Merge a list of spatial Seurat objects
aegis_example
Example Seurat object derived from Human Lymph Node data
aegis_default_markers()
Default marker list used by AEGIS MVP
align_deconv_to_seurat()
Align a deconvolution matrix to Seurat spot order
read_deconv_table()
Read a generic deconvolution result table
read_rctd()
Read RCTD deconvolution outputs
read_spotlight()
Read SPOTlight deconvolution outputs
read_cell2location()
Read cell2location deconvolution outputs
read_card()
Read CARD deconvolution outputs
read_spatialdwls()
Read SpatialDWLS deconvolution outputs
read_stereoscope()
Read stereoscope deconvolution outputs
read_destvi()
Read DestVI deconvolution outputs
read_tangram()
Read Tangram mapping-derived composition outputs
read_stdeconvolve()
Read STdeconvolve outputs
read_dstg()
Read DSTG deconvolution outputs
read_stride()
Read STRIDE deconvolution outputs

Core object and simulation

run_aegis()
Run the standard AEGIS workflow with one function
run_deconvolution() run_aegis_full() run_spotlight() run_card() run_rctd() run_cell2location() run_destvi() run_tangram() run_stereoscope()
Unified deconvolution orchestration and method runners
get_supported_methods()
List supported deconvolution methods and execution modes
as_aegis()
Construct an AEGIS object
as_aegis_multi()
Construct a multi-sample AEGIS object
is_aegis()
AEGIS analysis object
is_aegis_multi()
Check if object is an AEGIS multi-sample object
split_aegis_by_sample()
Split an AEGIS object by sample
summarize_by_sample()
Summarize AEGIS results by sample
simulate_deconv_results()
Simulate deconvolution results for a Seurat spatial object

Audit and comparison

audit_basic()
Run basic quality audits on deconvolution matrices
audit_marker()
Run marker-based concordance audit
audit_spatial()
Run spatial smoothness audit
compare_methods()
Compare deconvolution methods
score_methods()
Score deconvolution methods from available audit evidence
rank_methods()
Rank methods from evidence dimensions
compute_consensus()
Compute consensus deconvolution profile

Visualization and reporting

plot_audit()
Plot audit outputs
plot_compare()
Plot method comparison and consensus outputs
plot_method_ranking()
Plot method ranking summary
plot_disagreement_map()
Plot spot-level consensus disagreement map
plot_consensus_confidence()
Plot spot-level consensus confidence map
render_report()
Render an AEGIS HTML report
render_report_batch()
Render one report per sample
build_aegis_example_data()
Build and save example data from raw Human Lymph Node files